Dr. Leah Fung is the Chief Executive Officer of Biotheryx and a member of our Board of Directors. Previously, as our Chief Scientific Officer, Dr. Fung was pivotal in the design and implementation of the Company’s PRODEGY protein degradation platform, which has generated a pipeline of first-in-class protein degraders. Dr. Fung created Biotheryx’s molecular glue screening library for novel neosubstrate discovery and directed research that resulted in more than 25 issued U.S. patents covering an extensive range of small molecule protein degraders. Prior, Dr. Fung served as Vice President of Medicinal Chemistry at NovoMedix, Associate Director of Medicinal Chemistry at Structural Genomix (acquired by Eli Lilly), and Assistant Director of Medicinal Chemistry at Structural Bioinformatics. Dr. Fung also held leadership positions in research at Signal Pharmaceuticals and Celgene. Additionally, she was among leading scientists who pioneered combinatorial chemistry technologies and has authored over 20 peer-reviewed publications. She is also co-inventor on more than 40 issued U.S. patents and hundreds of international patents. Dr. Fung received her Ph.D. in chemistry from the University of California, Irvine.

Dr. Jeremy Barton joined Biotheryx as Acting Chief Medical Officer in August 2023. He is responsible for the Company’s program development activities, including clinical and non-clinical operations, regulatory affairs and medical strategy. Dr. Barton has over 30 years of global oncology drug development experience. He previously served as Chief Medical Officer of Biogen (formerly Biogen Idec), eFFECTOR Therapeutics and Mirati Therapeutics. Prior, he worked at Pfizer as Head of Oncology, Biotechnology Clinical Development, overseeing the transition of all oncology compounds from research through investigational new drug applications to proof of concept studies. Dr. Barton holds an M.S. in physiological sciences from Oxford University and an M.D. from University College Hospital Medical School in London. He trained in internal medicine and clinical oncology in the United Kingdom and practiced for 11 years in the National Health Service. Dr. Barton is Board Certified in internal medicine and clinical oncology, a member of the Royal College of Physicians in the United Kingdom, a fellow of the Royal College of Radiologists and a member of the Faculty of Pharmaceutical Medicine.

Dr. Aparajita Hoskote Chourasia joined Biotheryx in 2017. Dr. Chourasia was previously Vice President of Biology in October 2021, Vice President of Preclinical and Translational Biology in April 2023, and became Senior Vice President of Development and Biology in January 2024. Aparajita leads the full preclinical biology effort for development of targeted protein degraders at Biotheryx. She has been instrumental in identifying targets and establishing assays to assist in drug discovery efforts and has contributed to the development of the Company’s intellectual property. She has accrued expertise in molecular pathways in cancer, tumor metabolism, tumor models, inflammation and assay development while working at Veridex (a Johnson & Johnson company), Novartis Institutes for Biomedical Research and the Brigham and Women Hospital (teaching affiliate of Harvard Medical School). Dr. Chourasia earned her Ph.D. in cancer biology from the University of Chicago, where her research focused on the tumor suppressive function of BNIP3 mediated mitochondrial autophagy in mammary and 
pancreatic tumorigenesis and its potential as a critical biomarker for early-stage disease diagnosis. Her work led to successful NIH-funded research awards and peer reviewed research articles and reviews. Dr. Chourasia received an M.S. in biochemistry and molecular biology from the University of Illinois, Chicago, and an M.S. in translational science from Howard Hughes Medical Institute.

Dr. Shenlin Huang joined Biotheryx as Senior Director of Chemistry in June 2022. He became Executive Director of Chemistry in January 2024. Shenlin oversees the Company’s Medicinal Chemistry department, including database, computational chemistry and ADME/PK research. He previously served as Group Leader at AbbVie Oncology Discovery, where he led the company’s protein degradation program. Prior, Shenlin worked as Senior Research Investigator at Novartis Institutes for BioMedical Research where his team designed, synthesized and developed the FDA approved drug BRAFTOVI®. During this time, he also contributed to the development of several other clinical compounds. Prior, Shenlin was Senior Scientist at Johnson and Johnson Pharmaceutical. Dr. Huang received his Ph.D. in organic chemistry at the University of South Carolina and conducted his postdoctoral training at North Carolina State University.

David Pieters joined Biotheryx in 2021 and became the Senior Director of Finance and Accounting in August 2023. David is responsible for leading the Company’s finance function. He previously held various finance roles in the biopharmaceutical industry, mostly with publicly traded companies. Prior, he worked at Mayer Hoffman McCann P.C. in the audit and assurance practice. David holds a B.S. in accounting from the University of the Free State in South Africa and an M.S. in accounting from San Diego State University. David is a CPA licensed in California.

Dr. Arvind Shakya joined Biotheryx in 2022 and became Director of Pharmacology in March 2023. He is responsible for conducting the Company’s preclinical and translational in vivo pharmacology studies. Dr. Shakya previously served as Principal Scientist at Celgene, where he provided pharmacology support to the molecular glue, bifunctional degrader and inhibitor programs. He has more than 15 years of experience developing immunology and oncology animal models as well as GEM models to support preclinical, translational and toxicological studies. Dr. Shakya received a DVM (BVSc and AH) from India and a Ph.D. from the University of Missouri-Columbia. He conducted postdoctoral research at the University of Utah.

Dr. Venkat Mali joined Biotheryx as Director of Medicinal Chemistry in July 2022. Dr. Mali supports the Company’s discovery of targeted protein degradation-based drugs and molecular glue discovery programs. He previously worked at AbbVie, where he was a part of the team that discovered BTK degrader, ABBV-101. Prior, Dr. Mali worked at ChemoCentryx and Metabasis Therapeutics. At ChemoCentryx, he supported the discovery of small molecule drug candidates, which resulted in an FDA-approved drug, TAVNEOS™, three Phase 2 clinical compounds and one Phase 1 clinical compound. Additionally, Venkat has co-authored 48 publications and patents. Dr. Mali received a Ph.D. from the Indian Institute of Chemical Technology, Hyderabad, in synthetic organic chemistry. He conducted his postdoctoral research at the Scripps Research Institute.